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Transcriptional Basis for the Inhibition of Neural Stem Cell Proliferation and Migration by the TGFβ-Family Member GDF11

Signalling through EGF, FGF and endocannabinoid (eCB) receptors promotes adult neurogenesis, and this can be modelled in culture using the Cor-1 neural stem cell line. In the present study we show that Cor-1 cells express a TGFβ receptor complex composed of the ActRIIB/ALK5 subunits and that a natur...

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Detalles Bibliográficos
Autores principales: Williams, Gareth, Zentar, Marc P., Gajendra, Sangeetha, Sonego, Martina, Doherty, Patrick, Lalli, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820543/
https://www.ncbi.nlm.nih.gov/pubmed/24244313
http://dx.doi.org/10.1371/journal.pone.0078478