The BRCA1 Breast Cancer Suppressor: Regulation of Transport, Dynamics, and Function at Multiple Subcellular Locations

Inherited mutations in the BRCA1 gene predispose to a higher risk of breast/ovarian cancer. The BRCA1 tumor suppressor is a 1863 amino acid protein with multiple protein interaction domains that facilitate its roles in regulating DNA repair and maintenance, cell cycle progression, transcription, and...

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Detalles Bibliográficos
Autor principal: Henderson, Beric R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820561/
https://www.ncbi.nlm.nih.gov/pubmed/24278741
http://dx.doi.org/10.6064/2012/796808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820561/
https://www.ncbi.nlm.nih.gov/pubmed/24278741
http://dx.doi.org/10.6064/2012/796808

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