WSX-1 Signalling Inhibits CD4(+) T Cell Migration to the Liver during Malaria Infection by Repressing Chemokine-Independent Pathways

IL-27 is an important and non-redundant regulator of effector T cell accumulation in non-lymphoid tissues during infection. Using malaria as a model systemic pro-inflammatory infection, we demonstrate that the aberrant accumulation of CD4(+) T cells in the liver of infected IL27R(−/−) (WSX-1(−/−)) m...

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Detalles Bibliográficos
Autores principales: Villegas-Mendez, Ana, Gwyer Findlay, Emily, de Souza, J. Brian, Grady, Lisa-Marie, Saris, Christiaan J., Lane, Thomas E., Riley, Eleanor M., Couper, Kevin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820588/
https://www.ncbi.nlm.nih.gov/pubmed/24244314
http://dx.doi.org/10.1371/journal.pone.0078486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820588/
https://www.ncbi.nlm.nih.gov/pubmed/24244314
http://dx.doi.org/10.1371/journal.pone.0078486

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