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The Homeobox Gene MEIS1 Is Methylated in BRAF (p.V600E) Mutated Colon Tumors

Development of colorectal cancer (CRC) can occur both via gene mutations in tumor suppressor genes and oncogenes, as well as via epigenetic changes, including DNA methylation. Site-specific methylation in CRC regulates expression of tumor-associated genes. Right-sided colon tumors more frequently ha...

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Detalles Bibliográficos
Autores principales: Dihal, Ashwin A., Boot, Arnoud, van Roon, Eddy H., Schrumpf, Melanie, Fariña-Sarasqueta, Arantza, Fiocco, Marta, Zeestraten, Eliane C. M., Kuppen, Peter J. K., Morreau, Hans, van Wezel, Tom, Boer, Judith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820613/
https://www.ncbi.nlm.nih.gov/pubmed/24244575
http://dx.doi.org/10.1371/journal.pone.0079898