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The Homeobox Gene MEIS1 Is Methylated in BRAF (p.V600E) Mutated Colon Tumors
Development of colorectal cancer (CRC) can occur both via gene mutations in tumor suppressor genes and oncogenes, as well as via epigenetic changes, including DNA methylation. Site-specific methylation in CRC regulates expression of tumor-associated genes. Right-sided colon tumors more frequently ha...
Autores principales: | Dihal, Ashwin A., Boot, Arnoud, van Roon, Eddy H., Schrumpf, Melanie, Fariña-Sarasqueta, Arantza, Fiocco, Marta, Zeestraten, Eliane C. M., Kuppen, Peter J. K., Morreau, Hans, van Wezel, Tom, Boer, Judith M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820613/ https://www.ncbi.nlm.nih.gov/pubmed/24244575 http://dx.doi.org/10.1371/journal.pone.0079898 |
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