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Targeting Myeloid Cells to the Brain Using Non-Myeloablative Conditioning

Bone marrow-derived cells (BMDCs) are able to colonize the central nervous system (CNS) at sites of damage. This ability makes BMDCs an ideal cellular vehicle for transferring therapeutic genes/molecules to the CNS. However, conditioning is required for bone marrow-derived myeloid cells to engraft i...

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Detalles Bibliográficos
Autores principales: Böttcher, Chotima, Fernández-Klett, Francisco, Gladow, Nadine, Rolfes, Simone, Priller, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820653/
https://www.ncbi.nlm.nih.gov/pubmed/24244666
http://dx.doi.org/10.1371/journal.pone.0080260