A Role for Host Activation-Induced Cytidine Deaminase in Innate Immune Defense against KSHV

Activation-induced cytidine deaminase (AID) is specifically induced in germinal center B cells to carry out somatic hypermutation and class-switch recombination, two processes responsible for antibody diversification. Because of its mutagenic potential, AID expression and activity are tightly regula...

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Detalles Bibliográficos
Autores principales: Bekerman, Elena, Jeon, Diana, Ardolino, Michele, Coscoy, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820765/
https://www.ncbi.nlm.nih.gov/pubmed/24244169
http://dx.doi.org/10.1371/journal.ppat.1003748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820765/
https://www.ncbi.nlm.nih.gov/pubmed/24244169
http://dx.doi.org/10.1371/journal.ppat.1003748

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