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Fission Yeast Shelterin Regulates DNA Polymerases and Rad3(ATR) Kinase to Limit Telomere Extension

Studies in fission yeast have previously identified evolutionarily conserved shelterin and Stn1-Ten1 complexes, and established Rad3(ATR)/Tel1(ATM)-dependent phosphorylation of the shelterin subunit Ccq1 at Thr93 as the critical post-translational modification for telomerase recruitment to telomeres...

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Detalles Bibliográficos
Autores principales: Chang, Ya-Ting, Moser, Bettina A., Nakamura, Toru M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820796/
https://www.ncbi.nlm.nih.gov/pubmed/24244195
http://dx.doi.org/10.1371/journal.pgen.1003936