IL-18-based combinatorial adjuvants promote the intranodal production of CCL19 by NK cells and dendritic cells of cancer patients

The effective accumulation and interaction of mature dendritic cells (DCs) and naïve T cells within lymph nodes (LNs), which are driven by the CCR7-CCL19/CCL21 chemokine axis, are critical for the induction of adaptive T-cell immunity. Human natural killer (NK) cells activated by interleukin (IL)-18...

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Detalles Bibliográficos
Autores principales: Wong, Jeffrey L, Muthuswamy, Ravikumar, Bartlett, David L, Kalinski, Pawel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820810/
https://www.ncbi.nlm.nih.gov/pubmed/24228233
http://dx.doi.org/10.4161/onci.26245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820810/
https://www.ncbi.nlm.nih.gov/pubmed/24228233
http://dx.doi.org/10.4161/onci.26245

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