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Biochemical Analysis of the Plasmodium falciparum Erythrocyte-binding Antigen-175 (EBA175)-Glycophorin-A Interaction: IMPLICATIONS FOR VACCINE DESIGN

PfEBA175 has an important role in the invasion of human erythrocytes by Plasmodium falciparum and is therefore considered a high priority blood-stage malaria vaccine candidate. PfEBA175 mediates adhesion to erythrocytes through binding of the Duffy-binding-like (DBL) domains in its extracellular dom...

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Detalles Bibliográficos
Autores principales: Wanaguru, Madushi, Crosnier, Cécile, Johnson, Steven, Rayner, Julian C., Wright, Gavin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820850/
https://www.ncbi.nlm.nih.gov/pubmed/24043627
http://dx.doi.org/10.1074/jbc.M113.484840