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A Core MRB1 Complex Component Is Indispensable for RNA Editing in Insect and Human Infective Stages of Trypanosoma brucei

Uridine insertion/deletion RNA editing is a unique and vital process in kinetoplastids, required for creation of translatable open reading frames in most mitochondrially-encoded RNAs. Emerging as a key player in this process is the mitochondrial RNA binding 1 (MRB1) complex. MRB1 comprises an RNA-in...

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Detalles Bibliográficos
Autores principales: Ammerman, Michelle L., Tomasello, Danielle L., Faktorová, Drahomíra, Kafková, Lucie, Hashimi, Hassan, Lukeš, Julius, Read, Laurie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820961/
https://www.ncbi.nlm.nih.gov/pubmed/24250748
http://dx.doi.org/10.1371/journal.pone.0078015