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Germline Amino Acid Diversity in B Cell Receptors is a Good Predictor of Somatic Selection Pressures
The diversity of the immune repertoire is important for the adaptive immune system’s ability to detect pathogens. Much of this diversity is generated in two steps, first through the recombination of germline gene segments and second through hypermutation during an immune response. While both steps a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820969/ https://www.ncbi.nlm.nih.gov/pubmed/24265630 http://dx.doi.org/10.3389/fimmu.2013.00357 |