Essential yet limited role for CCR2(+) inflammatory monocytes during Mycobacterium tuberculosis-specific T cell priming

Defense against infection by Mycobacterium tuberculosis (Mtb) is mediated by CD4 T cells. CCR2(+) inflammatory monocytes (IMs) have been implicated in Mtb-specific CD4 T cell responses but their in vivo contribution remains unresolved. Herein, we show that transient ablation of IMs during infection...

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Detalles Bibliográficos
Autores principales: Samstein, Miriam, Schreiber, Heidi A, Leiner, Ingrid M, Sušac, Bože, Glickman, Michael S, Pamer, Eric G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820971/
https://www.ncbi.nlm.nih.gov/pubmed/24220507
http://dx.doi.org/10.7554/eLife.01086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820971/
https://www.ncbi.nlm.nih.gov/pubmed/24220507
http://dx.doi.org/10.7554/eLife.01086

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