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Essential yet limited role for CCR2(+) inflammatory monocytes during Mycobacterium tuberculosis-specific T cell priming
Defense against infection by Mycobacterium tuberculosis (Mtb) is mediated by CD4 T cells. CCR2(+) inflammatory monocytes (IMs) have been implicated in Mtb-specific CD4 T cell responses but their in vivo contribution remains unresolved. Herein, we show that transient ablation of IMs during infection...
Autores principales: | Samstein, Miriam, Schreiber, Heidi A, Leiner, Ingrid M, Sušac, Bože, Glickman, Michael S, Pamer, Eric G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820971/ https://www.ncbi.nlm.nih.gov/pubmed/24220507 http://dx.doi.org/10.7554/eLife.01086 |
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