Cargando…

Hepatitis B virus reverse transcriptase: diverse functions as classical and emerging targets for antiviral intervention

Hepatitis B virus (HBV) infection remains a global health problem with over 350 million chronically infected, causing an increased risk of cirrhosis and hepatocellular carcinoma. Current antiviral chemotherapy for HBV infection include five nucleos(t)ide analog reverse transcriptase inhibitors (NRTI...

Descripción completa

Detalles Bibliográficos
Autores principales: Jones, Scott A, Hu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820986/
https://www.ncbi.nlm.nih.gov/pubmed/26038488
http://dx.doi.org/10.1038/emi.2013.56