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Roles of PI3K/AKT/PTEN Pathway as a Target for Pharmaceutical Therapy
Multiple enzymes participate in the phosphorylation of a group of phosphoinositide lipids. Because of their important role in signal transduction, the dysregulated metabolism of phosphoinositides represents a key step in many disease settings. Loss of their function has been demonstrated to occur as...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Open
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821079/ https://www.ncbi.nlm.nih.gov/pubmed/24222802 http://dx.doi.org/10.2174/1874104501307010023 |