Position of UNC-13 in the active zone regulates synaptic vesicle release probability and release kinetics

The presynaptic active zone proteins UNC-13/Munc13s are essential for synaptic vesicle (SV) exocytosis by directly interacting with SV fusion apparatus. An open question is how their association with active zones, hence their position to Ca(2+) entry sites, regulates SV release. The N-termini of maj...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Keming, Stawicki, Tamara M, Goncharov, Alexandr, Jin, Yishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821175/
https://www.ncbi.nlm.nih.gov/pubmed/24220508
http://dx.doi.org/10.7554/eLife.01180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821175/
https://www.ncbi.nlm.nih.gov/pubmed/24220508
http://dx.doi.org/10.7554/eLife.01180

Ejemplares similares