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Reduction of influenza virus-induced lung inflammation and mortality in animals treated with a phosophodisestrase-4 inhibitor and a selective serotonin reuptake inhibitor

Inflammatory responses contribute to the morbidity and mortality of severe influenza. Current antiviral therapy offers limited success in treating severe influenza infection with both H1N1 and H5N1 viruses. We evaluated the effect of a neuraminidase inhibitor in combination with immunomodulatory dru...

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Detalles Bibliográficos
Autores principales: Sharma, Geeta, Champalal Sharma, Danilal, Hwei Fen, Leong, Pathak, Mukta, Bethur, Nijaguna, Pendharkar, Vishal, Peiris, Malik, Altmeyer, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821288/
https://www.ncbi.nlm.nih.gov/pubmed/26038487
http://dx.doi.org/10.1038/emi.2013.52