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Reduction of influenza virus-induced lung inflammation and mortality in animals treated with a phosophodisestrase-4 inhibitor and a selective serotonin reuptake inhibitor
Inflammatory responses contribute to the morbidity and mortality of severe influenza. Current antiviral therapy offers limited success in treating severe influenza infection with both H1N1 and H5N1 viruses. We evaluated the effect of a neuraminidase inhibitor in combination with immunomodulatory dru...
Autores principales: | Sharma, Geeta, Champalal Sharma, Danilal, Hwei Fen, Leong, Pathak, Mukta, Bethur, Nijaguna, Pendharkar, Vishal, Peiris, Malik, Altmeyer, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821288/ https://www.ncbi.nlm.nih.gov/pubmed/26038487 http://dx.doi.org/10.1038/emi.2013.52 |
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