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CO(2) directly modulates connexin 26 by formation of carbamate bridges between subunits

Homeostatic regulation of the partial pressure of CO(2) (PCO(2)) is vital for life. Sensing of pH has been proposed as a sufficient proxy for determination of PCO(2) and direct CO(2)-sensing largely discounted. Here we show that connexin 26 (Cx26) hemichannels, causally linked to respiratory chemose...

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Detalles Bibliográficos
Autores principales: Meigh, Louise, Greenhalgh, Sophie A, Rodgers, Thomas L, Cann, Martin J, Roper, David I, Dale, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821526/
https://www.ncbi.nlm.nih.gov/pubmed/24220509
http://dx.doi.org/10.7554/eLife.01213