Histone Deacetylase Inhibition Downregulates Collagen 3A1 in Fibrotic Lung Fibroblasts

Idiopathic pulmonary fibrosis (IPF) is a deadly disease characterized by chronic inflammation and excessive collagen accumulation in the lung. Myofibroblasts are the primary collagen-producing cells in pulmonary fibrosis. Histone deacetylase inhibitor (HDACi) can affect gene expression, and some, su...

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Detalles Bibliográficos
Autores principales: Zhang, Xiangyu, Liu, Hui, Hock, Thomas, Thannickal, Victor J., Sanders, Yan Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821575/
https://www.ncbi.nlm.nih.gov/pubmed/24084714
http://dx.doi.org/10.3390/ijms141019605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821575/
https://www.ncbi.nlm.nih.gov/pubmed/24084714
http://dx.doi.org/10.3390/ijms141019605

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