Cargando…
Histone Deacetylase Inhibition Downregulates Collagen 3A1 in Fibrotic Lung Fibroblasts
Idiopathic pulmonary fibrosis (IPF) is a deadly disease characterized by chronic inflammation and excessive collagen accumulation in the lung. Myofibroblasts are the primary collagen-producing cells in pulmonary fibrosis. Histone deacetylase inhibitor (HDACi) can affect gene expression, and some, su...
Autores principales: | Zhang, Xiangyu, Liu, Hui, Hock, Thomas, Thannickal, Victor J., Sanders, Yan Y. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821575/ https://www.ncbi.nlm.nih.gov/pubmed/24084714 http://dx.doi.org/10.3390/ijms141019605 |
Ejemplares similares
-
Modulation of H4K16Ac levels reduces pro-fibrotic gene expression and mitigates lung fibrosis in aged mice
por: Zhang, Xiangyu, et al.
Publicado: (2022) -
NOTCH-ing up Surface Tension in the Fibrotic Lung
por: Lasky, Joseph A., et al.
Publicado: (2022) -
Histone Modifications in Senescence-Associated Resistance to Apoptosis by Oxidative Stress()()
por: Sanders, Yan Y., et al.
Publicado: (2013) -
Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts
por: Huang, S K, et al.
Publicado: (2013) -
Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli
por: Dodi, Amos E., et al.
Publicado: (2018)