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Generation of an ICF Syndrome Model by Efficient Genome Editing of Human Induced Pluripotent Stem Cells Using the CRISPR System

Genome manipulation of human induced pluripotent stem (iPS) cells is essential to achieve their full potential as tools for regenerative medicine. To date, however, gene targeting in human pluripotent stem cells (hPSCs) has proven to be extremely difficult. Recently, an efficient genome manipulation...

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Detalles Bibliográficos
Autores principales: Horii, Takuro, Tamura, Daiki, Morita, Sumiyo, Kimura, Mika, Hatada, Izuho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821585/
https://www.ncbi.nlm.nih.gov/pubmed/24084724
http://dx.doi.org/10.3390/ijms141019774