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Molecular Study of a Hoxa2 Gain-of-Function in Chondrogenesis: A Model of Idiopathic Proportionate Short Stature

In a previous study using transgenic mice ectopically expressing Hoxa2 during chondrogenesis, we associated the animal phenotype to human idiopathic proportionate short stature. Our analysis showed that this overall size reduction was correlated with a negative influence of Hoxa2 at the first step o...

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Detalles Bibliográficos
Autores principales: Deprez, Pierre M. L., Nichane, Miloud G., Lengelé, Benoît G., Rezsöhazy, René, Nyssen-Behets, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821620/
https://www.ncbi.nlm.nih.gov/pubmed/24129174
http://dx.doi.org/10.3390/ijms141020386