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β-Arrestin Regulation of Myosin Light Chain Phosphorylation Promotes AT1aR-mediated Cell Contraction and Migration

Over the last decade, it has been established that G-protein-coupled receptors (GPCRs) signal not only through canonical G-protein-mediated mechanisms, but also through the ubiquitous cellular scaffolds β-arrestin-1 and β-arrestin-2. Previous studies have implicated β-arrestins as regulators of acti...

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Detalles Bibliográficos
Autores principales: Simard, Elie, Kovacs, Jeffrey J., Miller, William E., Kim, Jihee, Grandbois, Michel, Lefkowitz, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821855/
https://www.ncbi.nlm.nih.gov/pubmed/24255721
http://dx.doi.org/10.1371/journal.pone.0080532