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DOK2 Inhibits EGFR-Mutated Lung Adenocarcinoma

Somatic mutations in the EGFR proto-oncogene occur in ~15% of human lung adenocarcinomas and the importance of EGFR mutations for the initiation and maintenance of lung cancer is well established from mouse models and cancer therapy trials in human lung cancer patients. Recently, we identified DOK2...

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Detalles Bibliográficos
Autores principales: Berger, Alice H., Chen, Ming, Morotti, Alessandro, Janas, Justyna A., Niki, Masaru, Bronson, Roderick T., Taylor, Barry S., Ladanyi, Marc, Van Aelst, Linda, Politi, Katerina, Varmus, Harold E., Pandolfi, Pier Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821857/
https://www.ncbi.nlm.nih.gov/pubmed/24255704
http://dx.doi.org/10.1371/journal.pone.0079526