Collagen Content in Skin and Internal Organs of the Tight Skin Mouse: An Animal Model of Scleroderma

The Tight Skin mouse is a genetically induced animal model of tissue fibrosis caused by a large in-frame mutation in the gene encoding fibrillin-1 (Fbn-1). We examined the influence of gender on the collagen content of tissues in C57BL/6J wild type (+/+) and mutant Tight Skin (Tsk/+) mice employing...

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Detalles Bibliográficos
Autores principales: Manne, Jayanthi, Markova, Marina, Siracusa, Linda D., Jimenez, Sergio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821901/
https://www.ncbi.nlm.nih.gov/pubmed/24260716
http://dx.doi.org/10.1155/2013/436053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821901/
https://www.ncbi.nlm.nih.gov/pubmed/24260716
http://dx.doi.org/10.1155/2013/436053

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