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Collagen Content in Skin and Internal Organs of the Tight Skin Mouse: An Animal Model of Scleroderma
The Tight Skin mouse is a genetically induced animal model of tissue fibrosis caused by a large in-frame mutation in the gene encoding fibrillin-1 (Fbn-1). We examined the influence of gender on the collagen content of tissues in C57BL/6J wild type (+/+) and mutant Tight Skin (Tsk/+) mice employing...
Autores principales: | Manne, Jayanthi, Markova, Marina, Siracusa, Linda D., Jimenez, Sergio A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821901/ https://www.ncbi.nlm.nih.gov/pubmed/24260716 http://dx.doi.org/10.1155/2013/436053 |
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