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Mechanism and consequence of the autoactivation p38α Mitogen-activated Protein Kinase promoted by TAB1

p38α Mitogen-activated Protein Kinase (p38α) is activated by a variety of mechanisms, including autophosphorylation initiated by TGFβ-activated kinase 1 binding protein 1 (TAB1) during myocardial ischemia and other stresses. Chemical genetic approaches and co-expression in mammalian, bacterial and c...

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Detalles Bibliográficos
Autores principales: DeNicola, Gian Felice, Martin, Eva Denise, Chaikuad, Apirat, Bassi, Rekha, Clark, James, Martino, Luigi, Verma, Sharwari, Sicard, Pierre, Tata, Renée, Atkinson, R Andrew, Knapp, Stefan, Conte, Maria R, Marber, Michael S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822283/
https://www.ncbi.nlm.nih.gov/pubmed/24037507
http://dx.doi.org/10.1038/nsmb.2668