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The ubiquitin-proteasome system in Alzheimer's disease

Accumulation of proteins is a recurring event in many neurodegenerative diseases, including Alzheimer's disease (AD).Evidence has suggested that protein accumulation may result from a dysfunction in the ubiquitin proteasome system (UPS). Indeed, there is clear genetic and biochemical evidence o...

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Detalles Bibliográficos
Autor principal: Oddo, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822529/
https://www.ncbi.nlm.nih.gov/pubmed/18266959
http://dx.doi.org/10.1111/j.1582-4934.2008.00276.x