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The functions and possible significance of Kremen as the gatekeeper of Wnt signalling in development and pathology
Kremen (Krm) was originally discovered as a novel transmembrane protein containing the kringle domain. Both Krm1 (the first identified Krm) and its relative Krm2 were later identified to be the high-affinity receptors for Dickkopf (Dkk), the inhibitor of Wnt/β-catenin signalling. The formation of a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Blackwell Publishing Ltd
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822531/ https://www.ncbi.nlm.nih.gov/pubmed/18088386 http://dx.doi.org/10.1111/j.1582-4934.2007.00201.x |