Cargando…

High-resolution analysis of genetic stability of human adipose tissue stem cells cultured to senescence

The potential use of human mesenchymal stem cells for therapeutic applications implies large scale in vitro culture, increasing the probability of genetic instability and transformation. We examine here the incidence of unbalanced and balanced chromosome rearrangements in polyclonal and single cell-...

Descripción completa

Detalles Bibliográficos
Autores principales: Meza-Zepeda, Leonardo A, Noer, Agate, Dahl, John Arne, Micci, Francesca, Myklebost, Ola, Collas, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822542/
https://www.ncbi.nlm.nih.gov/pubmed/18419597
http://dx.doi.org/10.1111/j.1582-4934.2007.00146.x