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High-resolution analysis of genetic stability of human adipose tissue stem cells cultured to senescence
The potential use of human mesenchymal stem cells for therapeutic applications implies large scale in vitro culture, increasing the probability of genetic instability and transformation. We examine here the incidence of unbalanced and balanced chromosome rearrangements in polyclonal and single cell-...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822542/ https://www.ncbi.nlm.nih.gov/pubmed/18419597 http://dx.doi.org/10.1111/j.1582-4934.2007.00146.x |