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Oval cell proliferation in p16(INK4a) expressing mouse liver is triggered by chronic growth stimuli

Terminal differentiation requires molecules also involved in aging such as the cell cycle inhibitor p16(INK4a).Like other organs, the adult liver represents a quiescent organ with terminal differentiated cells, hepatocytes and cholangiocytes. These cells retain the ability to proliferate in response...

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Detalles Bibliográficos
Autores principales: Ueberham, Elke, Lindner, Ricco, Kamprad, Manja, Hiemann, Rico, Hilger, Nadja, Woithe, Barbara, Mahn, Doris, Cross, Michael, Sack, Ulrich, Gebhardt, Rolf, Arendt, Thomas, Ueberham, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822548/
https://www.ncbi.nlm.nih.gov/pubmed/18053084
http://dx.doi.org/10.1111/j.1582-4934.2007.00178.x