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Immunosuppression induced by immature dendritic cells is mediated by TGF-β/IL-10 double-positive CD4(+) regulatory T cells
Dendritic cells (DC) have important functions in T cell immunity and T cell tolerance. Previously, it was believed that T cell unresponsiveness induced by immature DC (iDC) is caused by the absence of inflammatory signals in steady-state in vivo conditions and by the low expression levels of costimu...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822554/ https://www.ncbi.nlm.nih.gov/pubmed/18419605 http://dx.doi.org/10.1111/j.1582-4934.2007.00084.x |