The roles of p27(Kip1) and DNA damage signalling in the chemotherapy-induced delayed cell cycle checkpoint

DNA lesions trigger the DNA damage response (DDR) machinery, which protects genomic integrity and sustains cellular survival. Increasing data underline the significance of the integrity of the DDR pathway in chemotherapy response. According to a recent work, persistent exposure of A549 lung carcinom...

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Detalles Bibliográficos
Autores principales: Liontos, Michalis, Velimezi, Georgia, Pateras, Ioannis S, Angelopoulou, Roxani, Papavassiliou, Athanasios G, Bartek, Jiri, Gorgoulis, Vassilis G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Point of View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822566/
https://www.ncbi.nlm.nih.gov/pubmed/20716117
http://dx.doi.org/10.1111/j.1582-4934.2010.01145.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822566/
https://www.ncbi.nlm.nih.gov/pubmed/20716117
http://dx.doi.org/10.1111/j.1582-4934.2010.01145.x

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