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MicroRNA-126 regulates the induction and function of CD4(+) Foxp3(+) regulatory T cells through PI3K/AKT pathway

Recent evidence showed that limited activation of PI3K/Akt pathway was critical for induction and function sustainment of CD4(+)Foxp3(+) regulatory T cells (Tregs). However, the underlying mechanism remains largely unknown. In this study, we reported that miR-126 was expressed in mouse and human Tre...

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Detalles Bibliográficos
Autores principales: Qin, Andong, Wen, Zhenke, Zhou, Ya, Li, Ying, Li, Yongju, Luo, Junmin, Ren, Tao, Xu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822588/
https://www.ncbi.nlm.nih.gov/pubmed/23301798
http://dx.doi.org/10.1111/jcmm.12003