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Rac1 activation induces tumour necrosis factor-α expression and cardiac dysfunction in endotoxemia
Induction of tumour necrosis factor-α (TNF-α) expression leads to myocardial depression during sepsis. However, the underlying molecular mechanisms are not fully understood. The aim of this study was to investigate the role of Rac1 in TNF-α expression and cardiac dysfunction during endotoxemia and t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822624/ https://www.ncbi.nlm.nih.gov/pubmed/20518848 http://dx.doi.org/10.1111/j.1582-4934.2010.01095.x |