Cargando…
Rac1 activation induces tumour necrosis factor-α expression and cardiac dysfunction in endotoxemia
Induction of tumour necrosis factor-α (TNF-α) expression leads to myocardial depression during sepsis. However, the underlying molecular mechanisms are not fully understood. The aim of this study was to investigate the role of Rac1 in TNF-α expression and cardiac dysfunction during endotoxemia and t...
Autores principales: | Zhang, Ting, Lu, Xiangru, Beier, Frank, Feng, Qingping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822624/ https://www.ncbi.nlm.nih.gov/pubmed/20518848 http://dx.doi.org/10.1111/j.1582-4934.2010.01095.x |
Ejemplares similares
-
The activation of EGFR promotes myocardial tumor necrosis factor-α production and cardiac failure in endotoxemia
por: Sun, Xuegang, et al.
Publicado: (2015) -
Rac1 Signaling Is Critical to Cardiomyocyte Polarity and Embryonic Heart Development
por: Leung, Carmen, et al.
Publicado: (2014) -
Rac1 Signaling Is Required for Anterior Second Heart Field Cellular Organization and Cardiac Outflow Tract Development
por: Leung, Carmen, et al.
Publicado: (2015) -
Tumor Necrosis Factor-α Mediates Lung Injury in the Early Phase of Endotoxemia
por: Chen, Kung-Yen, et al.
Publicado: (2022) -
Myocardium-Specific Deletion of Rac1 Causes Ventricular Noncompaction and Outflow Tract Defects
por: Leung, Carmen, et al.
Publicado: (2021)