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Pharmacological modulation of beta-catenin and its applications in cancer therapy

Beta-catenin (β-catenin) is a multifunction protein with a central role in physiological homeostasis. Its abnormal expression leads to various diseases including cancer. In normal physiology, β-catenin either maintains integrity of epithelial tissues or controls transcription of various genes on ext...

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Detalles Bibliográficos
Autores principales: Thakur, Ravi, Mishra, Durga Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822645/
https://www.ncbi.nlm.nih.gov/pubmed/23490077
http://dx.doi.org/10.1111/jcmm.12033