Cargando…

TNF-α inhibits aquaporin 5 expression in human salivary gland acinar cells via suppression of histone H4 acetylation

Sjögren's syndrome is a systemic autoimmune disease characterized by reductions in salivary and lacrimal secretions. The mechanisms underlying these reductions remain unclear. We have previously shown that TNF-α plays an important role in the destruction of acinar structures. Here we examined T...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamamura, Yoshiko, Motegi, Katsumi, Kani, Kouichi, Takano, Hideyuki, Momota, Yukihiro, Aota, Keiko, Yamanoi, Tomoko, Azuma, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822690/
https://www.ncbi.nlm.nih.gov/pubmed/21973049
http://dx.doi.org/10.1111/j.1582-4934.2011.01456.x