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Hypoxia-inducible factor 1–mediated human GATA1 induction promotes erythroid differentiation under hypoxic conditions

Hypoxia-inducible factor promotes erythropoiesis through coordinated cell type–specific hypoxia responses. GATA1 is essential to normal erythropoiesis and plays a crucial role in erythroid differentiation. In this study, we show that hypoxia-induced GATA1 expression is mediated by HIF1 in erythroid...

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Detalles Bibliográficos
Autores principales: Zhang, Feng-Lin, Shen, Guo-Min, Liu, Xiao-Ling, Wang, Fang, Zhao, Ying-Ze, Zhang, Jun-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822700/
https://www.ncbi.nlm.nih.gov/pubmed/22050843
http://dx.doi.org/10.1111/j.1582-4934.2011.01484.x