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Hypoxia-inducible factor 1–mediated human GATA1 induction promotes erythroid differentiation under hypoxic conditions
Hypoxia-inducible factor promotes erythropoiesis through coordinated cell type–specific hypoxia responses. GATA1 is essential to normal erythropoiesis and plays a crucial role in erythroid differentiation. In this study, we show that hypoxia-induced GATA1 expression is mediated by HIF1 in erythroid...
Autores principales: | Zhang, Feng-Lin, Shen, Guo-Min, Liu, Xiao-Ling, Wang, Fang, Zhao, Ying-Ze, Zhang, Jun-Wu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822700/ https://www.ncbi.nlm.nih.gov/pubmed/22050843 http://dx.doi.org/10.1111/j.1582-4934.2011.01484.x |
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