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Rapamycin inhibits transforming growth factor β-induced peritoneal angiogenesis by blocking the secondary hypoxic response

Patients with end-stage kidney disease on peritoneal dialysis often develop progressive scarring of the peritoneal tissues. This manifests as submesothelial thickening and is associated with increased vascularization that leads to ultrafiltration dysfunction. Hypoxia induces a characteristic series...

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Detalles Bibliográficos
Autores principales: Sekiguchi, Yoshimi, Zhang, Jing, Patterson, Sarah, Liu, Limin, Hamada, Chieko, Tomino, Yasuhiko, Margetts, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822704/
https://www.ncbi.nlm.nih.gov/pubmed/22117756
http://dx.doi.org/10.1111/j.1582-4934.2011.01493.x