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Rapamycin inhibits transforming growth factor β-induced peritoneal angiogenesis by blocking the secondary hypoxic response
Patients with end-stage kidney disease on peritoneal dialysis often develop progressive scarring of the peritoneal tissues. This manifests as submesothelial thickening and is associated with increased vascularization that leads to ultrafiltration dysfunction. Hypoxia induces a characteristic series...
Autores principales: | Sekiguchi, Yoshimi, Zhang, Jing, Patterson, Sarah, Liu, Limin, Hamada, Chieko, Tomino, Yasuhiko, Margetts, Peter J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822704/ https://www.ncbi.nlm.nih.gov/pubmed/22117756 http://dx.doi.org/10.1111/j.1582-4934.2011.01493.x |
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