BiP, an endoplasmic reticulum chaperone, modulates the development of morphine antinociceptive tolerance

Morphine is a potent analgesic, but the molecular mechanism for tolerance formation after repeated use is not fully understood. Binding immunoglobulin protein (BiP) is an endoplasmic reticulum (ER) chaperone that is central to ER function. We examined knock-in mice expressing a mutant BiP with the r...

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Detalles Bibliográficos
Autores principales: Dobashi, Tamae, Tanabe, Serabi, Jin, Hisayo, Mimura, Naoya, Yamamoto, Tatsuo, Nishino, Takashi, Aoe, Tomohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822731/
https://www.ncbi.nlm.nih.gov/pubmed/19818092
http://dx.doi.org/10.1111/j.1582-4934.2009.00932.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822731/
https://www.ncbi.nlm.nih.gov/pubmed/19818092
http://dx.doi.org/10.1111/j.1582-4934.2009.00932.x

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