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Establishment and characterization of scleroderma fibroblast clonal cell lines by introduction of the hTERT gene

Lack of an adequate experimental model has hindered the ability to fully understand scleroderma (SSc) pathogenesis. Current SSc research is based on the study of cultured fibroblasts from skin biopsies. In depth characterization of the SSc fibroblast phenotype is hindered by the limited lifespan and...

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Detalles Bibliográficos
Autores principales: Kapanadze, Bagrat, Morris, Erin, Smith, Edwin, Trojanowska, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822752/
https://www.ncbi.nlm.nih.gov/pubmed/19432820
http://dx.doi.org/10.1111/j.1582-4934.2009.00773.x