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Establishment and characterization of scleroderma fibroblast clonal cell lines by introduction of the hTERT gene
Lack of an adequate experimental model has hindered the ability to fully understand scleroderma (SSc) pathogenesis. Current SSc research is based on the study of cultured fibroblasts from skin biopsies. In depth characterization of the SSc fibroblast phenotype is hindered by the limited lifespan and...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822752/ https://www.ncbi.nlm.nih.gov/pubmed/19432820 http://dx.doi.org/10.1111/j.1582-4934.2009.00773.x |