Chimeric RXFP1 and RXFP2 Receptors Highlight the Similar Mechanism of Activation Utilizing Their N-Terminal Low-Density Lipoprotein Class A Modules

Relaxin family peptide (RXFP) receptors 1 and 2 are unique G-protein coupled receptors in that they contain an N-terminal low-density lipoprotein type A (LDLa) module which is necessary for receptor activation. The current hypothesis suggests that upon ligand binding the LDLa module interacts with t...

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Detalles Bibliográficos
Autores principales: Bruell, Shoni, Kong, Roy C. K., Petrie, Emma J., Hoare, Brad, Wade, John D., Scott, Daniel J., Gooley, Paul R., Bathgate, Ross A. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822782/
https://www.ncbi.nlm.nih.gov/pubmed/24273532
http://dx.doi.org/10.3389/fendo.2013.00171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822782/
https://www.ncbi.nlm.nih.gov/pubmed/24273532
http://dx.doi.org/10.3389/fendo.2013.00171

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