Cargando…
Targeting the telomere and shelterin complex for cancer therapy: current views and future perspectives
Aberrant telomere homeostasis is essential for cell immortality, enabling cells to evade telomere dependent senescence. Disruption of telomere structure and function in cancer cells is highly toxic as shown by detailed pre-clinical evaluation of telomerase inhibitors. Under telomerase inhibition, ce...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822786/ https://www.ncbi.nlm.nih.gov/pubmed/21199331 http://dx.doi.org/10.1111/j.1582-4934.2010.01253.x |