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Small leucine-rich proteoglycans in atherosclerotic lesions: novel targets of chronic statin treatment?

Small leucine-rich proteoglycans (SLRPs), such as decorin and biglycan, regulate the assembly and turnover of collagenous matrix. The aim of the study was to analyse the effect of chronic rosuvastatin treatment on decorin, biglycan and the collagen matrix in ApoE-deficient mice. Twenty-week-old male...

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Detalles Bibliográficos
Autores principales: Marzoll, Andrea, Melchior-Becker, Ariane, Cipollone, Francesco, Fischer, Jens W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822791/
https://www.ncbi.nlm.nih.gov/pubmed/20015203
http://dx.doi.org/10.1111/j.1582-4934.2009.00986.x